Ms. Jowell was diagnosed with a brain tumor previous year.
The dedicated former minister has been particularly praised for her success in bringing the Olympics to London and her campaigning on cancer research.
In her powerful and moving speech in the House of Lords, she also backed our campaign for 5-ALA - the so-called "pink drink", which causes brain tumour cells to glow in the dark and therefore makes them more easily visible to surgeons operating to remove them - to be made available across the United Kingdom to any patient who would benefit from its use.
She told peers: "In the end, what gives a life meaning is not only how it is lived, but how it draws to a close".
During a speech to the House of Lords in January, Jowell said: "I hope that this debate will give hope to other cancer patients, like me, so we can live well together with cancer, not just dying of it".
She died peacefully at the family home near Shipston-on-Stour in Warwickshire shortly after 22:00 BST on Saturday, the statement said.
Leading the tributes to his ex-minister, former prime minister Tony Blair said she was a "committed public servant" who was "always true and loyal and decent and wise".
"Her contribution to the Olympic and Paralympic Games is easily defined - without Tessa there would have been no London 2012, and without Tessa they would not have been the success they were". The following day - July 7, 2005 - four suicide bombers targeted the city's public transportation network, killing 52 people and injuring hundreds more. She was one of just a few politicians to serve as a Cabinet member for the full terms of Prime Ministers Tony Blair and Gordon Brown.
He added: "I kind of can't quite believe she's gone". "We were celebrating having won the Olympic bid when my private secretary received a call from London to be told that there might have been a terrorist attack on the Tube network".
Theresa May and the health secretary, Jeremy Hunt, also announced an annual Tessa Jowell global symposium, which will host the best clinical, scientific and academic minds on brain cancer to to identify gaps, best practice and research priorities. She lost to her Conservative rival and was defeated again the following year.
"My thoughts and prayers, and those of Cherie and all the family are with David and her wonderful family of whom she was justly very proud".
"So it was a deeply civilized thing that we did in those marvelous two weeks in the summer of 2012". In sport, soccer legend David Beckham posted an image on his Instagram feed that showed him giving her a hug.
Lord Sebastian Coe, former chairman of the London Organising Committee for the Olympic Games, said there would not have been a London 2012 without the contributions of Dame Tessa.
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